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Secret of Photo 51

Picturing the Molecules of Life

 

Intro | 1952: Photo 51 | 1973: Transfer RNA | 1979: "Left-handed" DNA | 1980: "Right-handed" DNA |  1984: Protein/DNA complex  | 2001: Ribosome

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Protein/DNA complex

In 1984, John Rosenberg of the University of Pittsburgh completed the first visualization of a protein/DNA complex—a molecule of DNA and a molecule of protein bound together. This complex involved the EcoR1 protein, an important enzyme that is known to bind to DNA. Protein/DNA complexes play an important part in many biological processes. The structure imaged here has helped scientists understand how protein and DNA molecules recognize each other.

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